Equipalazone (Bute) for Horses - 1g Sachet

Description

Equipalazone may only be supplied with a valid veterinary prescription issued by your vet. You should only purchase Equipalazone if you have or are in the process of arranging such a prescription. See information bar for further details.      

Equipalazone is a free flowing white owder for oral administration containing 1 g micro-encapsulated phenylbutazone per sachet. Preservative: sodium paracombin 0.15 % w/w

Equipalazone 1g oral powder is indicated in the treatment of musculoskeletal disorders in horses and ponies where the anti-inflammatory and analgesic properties of phenylbutazone can offer relief for example in lameness associated with osteoarthritic conditions acute and chronic laminitis bursitis and carpitis and in the reduction of post-surgical soft tissue reaction.

Dosage and administration
For oral administration only. Dependent on individual response but as a guide: Horses: 450 kg (1000 lb) body weight: Two sachets to be administered twice on day one (equivalent to 8.8 mg/kg/day) followed by one sachet twice daily for four days (4.4 mg/kg/day) then one sachet daily or on alternate days sufficient to keep the horse comfortable (2.2 mg/kg/day). Ponies: 225 kg (500 lb) body weight: One sachet (4.4 mg/kg/day) on alternate days. Adjust dose according to body weight. Discontinue treatment if no response is evident after four to five days treatment. Equipalazone 1 g oral powder should be mixed with a small quantity of feed.

Contra-indications warnings etc
Not to be used in horses intended for human consumption. Treated horses may never be slaughtered for human consumption. The horse must have been declared as not intended for human consumption under national horse passport legislation. The therapeutic index of phenylbutazone is low. Do not exceed the stated dose or the duration of treatment. Do not use in animals suffering from cardiac hepatic or renal disease where there is the possibility of gastrointestinal ulceration or bleeding or where there is evidence of a blood dyscrasia or hypersensitivity to the product. Do not administer other NSAIDs concurrently or within 24 hours of each other. Some NSAIDs may be highly bound to plasma proteins and compete with other highly bound drugs to produce an increase in non-bound pharmacologically active concentrations which can lead to toxic effects. Use in any animal less than six weeks of age or in aged animals may involve additional risk. If such use cannot be avoided animals may require a reduced dosage and careful clinical management. Avoid use in any dehydrated hypovolaemic or hypotensive animal as there is a risk of increased toxicity. Concurrent administration of potentially nephrotoxic drugs should be avoided. It is preferable that NSAIDs which inhibit prostaglandin synthesis are not administered to animals undergoing general anaesthesia until fully recovered. Gastrointestinal tract ulceration may be exacerbated by corticosteroids in animals given NSAIDs. Use during pregnancy should be avoided whenever possible particularly during the first trimester. Response to long-term therapy should be monitored at regular intervals by a veterinary practitioner. Operator warnings: The product should be handled with care at all times to reduce the risk of accidental ingestion skin contact or dust inhalation. If accidental skin or eye contact occurs the site should be washed immediately with water. If the product is ingested seek medical advice immediately and show the product packaging. Advice to doctors: gastric lavage (emesis in children) should be performed urgently. Charcoal haemoperfusion has also been shown to be beneficial. Treatment should then be administered symptomatically.

General precautions: For animal treatment only. NSAIDs can cause inhibition of phagocytosis and hence in the treatment of inflammatory conditions associated with bacterial infections appropriate concurrent antimicrobial therapy should be instigated. Withdrawal period: Not to be used in horses intended for human consumption. Treated horses may never be slaughtered for human consumption. The horse must have been declared as not intended for human consumption under national horse passport legislation.

Pharmaceutical precautions
Do not store above 25C. Store in a dry place. Keep out of the reach and sight of children. Disposal: Dispose of any unused product and empty containers in accordance with guidance from your national waste regulation authority.

Legal category
Equipalazone is a POM-V (Pet Prescription Required)