Incurin Tablet 1mg - Priced per Tablet
88341
Incurin is a prescription medication used to manage hormone-dependent urinary incontinence in female dogs. It contains estriol, a natural form of oestrogen, which helps restore control over bladder function. This medication is specifically designed for spayed female dogs experiencing involuntary urine leakage due to decreased oestrogen levels.
What is Hormone-Dependent Urinary Incontinence?
Hormone-dependent urinary incontinence is a common condition in spayed female dogs, typically occurring as they age. It results from a decline in oestrogen production following spaying. Oestrogen plays a crucial role in maintaining muscle tone in the urethral sphincter, which is responsible for preventing urine leakage.
When oestrogen levels drop, the muscles controlling urine retention weaken, leading to involuntary leakage. This condition is also known as urethral sphincter mechanism incompetence (USMI). It can cause noticeable symptoms such as small puddles of urine left behind where the dog has been lying down or sleeping. Leakage can be infrequent or more consistent, depending on the severity of the condition.
Although the condition is not painful, it can be distressing for both the dog and the owner. Affected dogs may not realise they are leaking urine, and owners may notice damp bedding or an ammonia-like odour. Without treatment, the condition can lead to skin irritation, infections, and hygiene concerns.
Product Features
- Pack Size: - Sold Individually
- Target Animal: - Dog (Canine)
- Related Condition: - The treatment of hormone-dependent urinary incontinence in dogs
- Pet Prescription Required?: - Yes
- Active Ingredient: - Estriol
- Product Name: - Incurin Tablet 1mg - Priced per Tablet
More Information
Description
Incurin for Dogs
Incurin may only be supplied with a valid veterinary prescription issued by your vet. You should only purchase Incurin if you have or are in the process of arranging such a prescription. See information bar for further details.
How Does Incurin Work?
Incurin contains estriol, a short-acting, naturally occurring oestrogen. This hormone helps to restore urethral sphincter muscle tone, improving the ability to retain urine. Unlike other synthetic oestrogens, estriol has a short half-life, reducing the risk of long-term side effects.
Once administered, the active ingredient is absorbed into the bloodstream, binding to oestrogen receptors in the bladder and urinary tract. This interaction helps strengthen the urethral sphincter, reducing the frequency and severity of urine leakage.
The medication is typically given once daily as prescribed by a veterinarian. The dosage is adjusted based on the dog’s response to treatment. Many dogs show improvement within days, though some may require a few weeks to achieve full effectiveness. Once the desired effect is reached, the dose may be reduced to the minimum necessary to maintain continence.
Who Can Use Incurin?
Incurin is intended for use in female dogs that have been spayed and are diagnosed with hormone-dependent urinary incontinence. It is not suitable for male dogs or intact females. It should not be used in dogs with certain medical conditions, including some forms of cancer, as oestrogen-sensitive tumours can be affected by hormone therapy.
A veterinarian will assess the dog’s health before prescribing Incurin to ensure it is a suitable treatment. Dogs with pre-existing liver disease, diabetes, or other hormonal imbalances may require additional monitoring during treatment.
How to Administer Incurin
Incurin is available in tablet form and is given orally once a day. The recommended starting dose is one tablet per day, but the dosage may be adjusted by the veterinarian based on the dog’s response. In some cases, the dose can be reduced to a maintenance level while still effectively controlling symptoms.
Tablets can be given with or without food, depending on the dog’s preference and tolerance. It is important to follow the prescribed dosage and not to exceed the recommended amount. If a dose is missed, it should be given as soon as possible, but double dosing should be avoided.
Possible Side Effects of Incurin
Most dogs tolerate Incurin well, but some may experience mild side effects as their body adjusts to the medication. The most common side effects include:
- Increased thirst and urination
- Swelling of the vulva
- Changes in appetite
- Behavioural changes, such as restlessness or agitation
These effects are usually temporary and resolve once the dosage is adjusted. If a dog experiences persistent or severe side effects, a veterinarian should be consulted. Long-term use of high doses of oestrogen can increase the risk of bone marrow suppression, but this risk is significantly reduced with the short-acting nature of estriol in Incurin.
Storage and Handling
Incurin should be stored in a cool, dry place, away from direct sunlight and moisture. The tablets should be kept in their original packaging to protect them from environmental factors. It is essential to store them out of reach of pets and children to prevent accidental ingestion.
Unused or expired medication should be disposed of according to veterinary guidance. It should not be flushed down the toilet or discarded in household waste, as improper disposal may pose a risk to the environment.
Precautions and Veterinary Monitoring
Regular veterinary check-ups are recommended during Incurin treatment to monitor the dog’s response and adjust the dosage if necessary. A veterinarian may conduct follow-up examinations to ensure the medication remains effective and to check for any potential side effects.
If symptoms persist despite treatment, further diagnostic tests may be needed to rule out other underlying conditions that could contribute to incontinence. Some cases of urinary leakage may be caused by urinary tract infections, neurological issues, or congenital abnormalities that require different treatments.
Legal category
Incurin is a POM-V (Pet Prescription Required)
Priced per individual tablet
Brand
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