150mg Masivet Tablets - Pot of 30

Description

150mg Masivet Tablets from the UK with Worldwide Delivery

Masivet may only be supplied with a valid veterinary prescription issued by your vet. You should only purchase Masivet if you have or are in the process of arranging such a prescription. See information bar for further details.

150mg Masivet (licensed as Kinavet in the USA) is a prescription-only tablet for use against Mast Cell Tumours in dogs. Masivet is regarded as safe enough to be used at home, and is given as a tablet once daily. Masivet acts against mast cell tumours, by inhibiting cell division, therefore preventing further development of the tumours. Not all dogs respond, but the results can be very helpful for others. Close veterinary supervision is recommended at all times.

Mast cell tumours are one of the most common skin tumours in dogs. They originate from mast cells, which are cells involved in allergic reactions. These tumours can vary in appearance, often resembling benign skin lumps or insect bites. The severity of mast cell tumours can range from benign to highly malignant, and early detection and treatment are crucial.

Masivet 150mg for Dogs is a targeted treatment specifically designed for mast cell tumours in dogs. Unlike other treatments that might attack or damage healthy tissues, 150mg Masivet Tablets are designed to act against the root cause of the tumour without harming healthy cells. This targeted approach to cancer management has revolutionised the way certain human cancers are treated and is now available for our canine friends.

Administered once daily in tablet form, 150mg Masivet for Dogs is considered safe enough for at-home administration. However, it's essential that dogs undergoing this treatment return to their veterinary clinic for regular monitoring and follow-up. Not all dogs may respond to the treatment, but for many, the results can be significantly beneficial.

While Masivet 150mg for Dogs offers a promising solution for dogs with mast cell tumours, it's essential to understand that it's available only on prescription via veterinary professionals. Before starting the treatment, a vet will assess the specific characteristics of the tumour to determine the best possible treatment options. If a tyrosine kinase inhibitor like Masivet is deemed appropriate, the vet will guide the pet owner on the correct dosage and administration.

What is Masivet?

150mg Masivet is a round, orange tablet containing 150mg masitinib, which belongs to a class of medicines having an anticancer action.

What is Masivet used for?

Masivet is used to treat dogs with mast-cell tumours (a type of cancer). It is used for tumours which are severe in character (grade 2 or 3) and which cannot be removed with surgery. Masivet is only used if the presence of a mutated form of the receptor protein c-kit in the tumours has been confirmed before the start of treatment. Masivet tablets are given by mouth, once a day. The dose of Masivet depends on the weight of the dog being treated.. The duration of treatment depends on the dog’s response to treatment.

Mast cell tumours (MCTs) are the most common cutaneous malignancies in dogs, accounting for 16% to 21% of all skin tumours. MCTs demonstrate a wide range of behaviours, appearance and patterns of progression – all of which make these tumours a challenge to treat.

Whilst surgery is always the first option and the cornerstone of MCT management, anti-cancer medical treatment is needed when complete surgical removal is not possible or where the tumour is highly aggressive or has already spread.

How does Masivet work?

The active substance in Masivet, masitinib, is a protein-tyrosine kinase inhibitor. This means that it blocks some specific enzymes known as tyrosine kinases. These enzymes can be found in some receptors on the surface of cells, including the c-kit receptor. Some types of mast-cell tumour are linked to a mutation that causes excessive action of c-kit and stimulates the mast cells to divide uncontrollably. By blocking these receptors, Masivet might help to control cell division, preventing further development of the tumours with this particular mutation.

How has Masivet been studied?

A number of studies with Masivet were carried out either in laboratory dogs or in animal patients at veterinary practises in Europe and in the USA. The main study compared the effectiveness of Masivet at the recommended dose of 12.5 mg per kilogramme bodyweight once a day with placebo (a dummy treatment). The study included dogs of various breeds and both sexes with mast-cell tumours that had come back after surgery or could not be removed with surgery. The study population included dogs whose tumours contained mutated or normal (‘wild-type’) c-kit receptors.

Legal Category

Masivet is a POM-V (Pet Prescription-only Medication)

150mg Masivet is used to treat dogs with mast-cell tumours (carcinomas), which are characterized by rapidly growing, highly vascular (blood filled) tumours. These tumours are a type of cancer that develops from white blood cells called mast cells. Masivet is a medicine used for treatment of mast cell tumours (a type of cancer). The medicine contains masitinib, which belongs to a class of medicines having an anti cancer action. It is available as round, orange tablets (50 and 150 mg).