
Pexion 400mg Tablet - per Tablet
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400mg Pexion is a prescription medication used to manage epilepsy in dogs. Each tablet contains 400mg of imepitoin, an antiepileptic drug that helps reduce the frequency and severity of seizures.
Pexion is primarily used to treat idiopathic epilepsy, a common neurological disorder in dogs. It may also be prescribed for dogs suffering from noise phobia, as it has calming effects on the nervous system. Unlike some traditional epilepsy medications, Pexion has a lower risk of liver toxicity and can be a suitable long-term treatment option for many dogs.
How Pexion Works
Pexion 400mg contains imepitoin, a drug that acts on the brain’s neurotransmitters to stabilise electrical activity and prevent seizures.
Seizures occur due to abnormal electrical signals in the brain, causing sudden and uncontrolled movements, loss of consciousness, or behavioural changes. Imepitoin works by enhancing the effects of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces excessive brain activity. By increasing GABA’s calming effects, Pexion helps to suppress abnormal electrical impulses and prevent seizure episodes.
Pexion also has anti-anxiety properties, which make it beneficial for dogs with noise-related anxiety, such as fear of fireworks or thunderstorms.
VET PRESCRIPION REQUIRED
Product Features
- Pack Size: - Sold Individually
- Target Animal: - Dog (Canine)
- Related Condition: - Epilepsy in Dogs
- Pet Prescription Required?: - Yes (For UK Orders)
- Active Ingredient: - Imepitoin
- Product Name: - Pexion 400mg Tablet - per Tablet
More Information
Description
Pexion may only be supplied with a valid veterinary prescription issued by your vet. You should only purchase Pexion if you have or are in the process of arranging such a prescription. See information bar for further details.
Understanding Epilepsy in Dogs
Epilepsy is one of the most common neurological disorders in dogs and is characterised by recurring seizures. It is a lifelong condition that requires ongoing management to maintain a good quality of life.
The most common type of epilepsy in dogs is idiopathic epilepsy, which has no identifiable underlying cause but is believed to be genetic. Other types of epilepsy may result from structural abnormalities in the brain, infections, or metabolic disorders.
Seizures can vary in severity and frequency. Some dogs experience occasional mild seizures, while others have frequent and severe episodes. Without proper treatment, epilepsy can impact a dog's overall health and well-being.
Signs of Epilepsy in Dogs
Seizures in dogs can present in different ways, depending on the severity of the episode. Common signs include:
- Sudden collapse or loss of consciousness
- Uncontrollable muscle twitching or jerking
- Stiffening of the body
- Paddling movements of the legs
- Excessive drooling or foaming at the mouth
- Unusual vocalisations, such as whining or howling
- Loss of bladder or bowel control
- Temporary confusion or disorientation after the seizure (postictal phase)
Some dogs may show behavioural changes before a seizure, such as restlessness, pacing, or seeking comfort from their owner. This is known as the preictal phase or "aura."
Causes and Risk Factors of Canine Epilepsy
Idiopathic epilepsy has no known cause but is believed to be hereditary in certain breeds. Some of the breeds more prone to epilepsy include:
- Border Collies
- Labrador Retrievers
- Golden Retrievers
- German Shepherds
- Beagles
- Belgian Malinois
Other factors that may contribute to seizures include:
- Head trauma
- Brain tumours
- Liver or kidney disease
- Exposure to toxins
- Infections affecting the brain
Dogs with epilepsy require lifelong management, and treatment with antiepileptic medication like Pexion can help reduce the severity and frequency of seizures.
Administering Pexion to Dogs
Pexion is available in 400mg tablets and should be given as prescribed by a veterinarian. The dosage is based on the dog’s weight and response to treatment.
Tablets should be administered orally, either directly into the dog’s mouth or mixed with food. Pexion is usually given twice daily, with at least 12 hours between doses. It is important to give the medication consistently and not miss doses, as this can increase the risk of seizures.
If a dose is missed, it should be given as soon as possible unless it is close to the next scheduled dose. Owners should not double the dose to make up for a missed one.
Expected Response to Pexion
Pexion does not provide an immediate cure for epilepsy but helps reduce the number and severity of seizures over time. Some dogs respond quickly, while others may require several weeks of consistent use before noticeable improvements occur.
Regular veterinary check-ups are essential to monitor progress and adjust the dosage if necessary. Some dogs may need lifelong medication, while others may require periodic adjustments based on seizure activity.
Possible Side Effects of Pexion
Most dogs tolerate Pexion well, but some may experience mild side effects, especially during the initial stages of treatment. These can include:
- Mild sedation or drowsiness
- Increased thirst and urination
- Temporary loss of appetite
- Unsteadiness or lack of coordination
In rare cases, some dogs may develop more serious reactions, such as aggression or gastrointestinal upset. If any unusual symptoms persist or worsen, a veterinarian should be consulted.
Precautions and Contraindications
Pexion is generally well tolerated, but certain precautions should be considered before starting treatment:
- Not suitable for dogs with severe liver disease – While Pexion has a lower risk of liver toxicity than some other epilepsy drugs, veterinary guidance is required for dogs with pre-existing liver conditions.
- Use with caution in pregnant or lactating dogs – The effects of Pexion on unborn or nursing puppies have not been fully studied.
- Should not be used in dogs with a history of severe aggression – Some dogs may experience changes in behaviour, so careful monitoring is required.
- Interaction with other medications – Pexion may interact with other antiepileptic drugs or sedatives. A veterinarian should be informed of all medications the dog is receiving.
Ongoing Management of Epilepsy
Epilepsy requires long-term management, and medication alone may not completely prevent seizures. Owners can take additional steps to help manage the condition, such as:
- Keeping a seizure diary to track episodes, triggers, and medication response.
- Avoiding known triggers, such as stress, flashing lights, or sudden loud noises.
- Ensuring the dog has a consistent routine, as changes in environment or diet can sometimes contribute to seizures.
- Providing a safe space for the dog during a seizure to prevent injury.
Regular veterinary check-ups are important to assess whether the current treatment plan is effective or if adjustments are needed.
Storage and Handling of Pexion
400mg Pexion tablets should be stored in a cool, dry place away from direct sunlight. The medication should be kept out of reach of children and other pets. Any unused or expired tablets should be disposed of safely, following veterinary or pharmacy guidance.
Pexion is a POM-V Medication (Pet Prescription Required)
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