80mg Tralieve Chewable Tramadol Tablets for Dogs - per Tablet

Description

80mg Tralieve - Pain relief for dogs

80mg Tralieve may only be supplied with a valid veterinary prescription issued by your vet. You should only purchase 80mg Tralieve if you have or are in the process of arranging such a prescription. See information bar for further details.

As this medication is a controlled drug we require that the ORIGINAL prescription is sent to us at: Vetmeds Ltd. Unit 2 Airfield Road Trading Estate, Airfield Road, Podington, Northamptonshire NN29 7XA.

Target species: Dogs

Indications for use, specifying the target species - 80mg Tralieve is used for the reduction of acute and chronic mild soft tissue and musculoskeletal pain.

Contraindications Do not administer 80mg Tralieve in conjunction with tricyclic antidepressants, monoamine oxidase inhibitors and serotonin reuptake inhibitors. Do not use in cases of hypersensitivity to tramadol or to any of the excipients. Do not use Tralieve in animals with epilepsy.

Special warnings The analgesic effects of tramadol hydrochloride (Tralieve) may be variable. This is thought to be due to individual differences in the metabolism of the drug to the primary active metabolite O-desmethyltramadol. In some dogs (non-responders) this may result in the product failing to provide analgesia. For chronic pain, multimodal analgesia should be considered. Dogs should be monitored regularly by a veterinarian to ensure adequate pain relief. In case of recurrence of pain or insufficient analgesia the analgesic protocol may need to be reconsidered

Special precautions for use - Use 80mg Tralieve with caution in dogs with renal or hepatic impairment. In dogs with hepatic impairment the metabolism of tramadol to the active metabolites may be decreased which may reduce the efficacy of Tralieve. One of the active metabolites of tramadol is renally excreted and therefore in dogs with renal impairment the dosing regimen used may need to be adjusted. Renal and hepatic function should be monitored when using this product. Cessation of long-term analgesic therapy should be done gradually whenever possible. Special precautions to be taken by the person administering the veterinary medicinal product to animals. 80mg Tralieve may cause sedation, nausea and dizziness after accidental ingestion, especially by children. To avoid accidental ingestion, particularly by a child, unused tablet parts should be returned to the open blister space and inserted back into the carton and kept in a safe place out of the sight and reach of children as they pose a health risk to small children due to accidental ingestion. In case of accidental ingestion, particularly by children, seek medical advice and show the package leaflet or the label to the physician. In case of accidental ingestion by adults: DO NOT DRIVE as sedation may occur. People with known hypersensitivity to tramadol or any of the excipients should avoid contact with the veterinary medicinal product. Wash hands after use.

Adverse reactions (frequency and seriousness) Mild sedation and drowsiness may commonly occur, especially when higher doses of Tralieve are given. Nausea and vomiting have uncommonly been observed in dogs after administration of Tralieve. In rare cases hypersensitivity can occur. In cases of hypersensitivity reactions the treatment should be discontinued.

80mg Tralieve can increase the effect of drugs that lower the seizure threshold. Drugs that inhibit (e.g. cimetidine and erythromycin) or induce (e.g. carbamazepine) CYP450 mediated metabolism may have an effect on the analgesic effect of tramadol. The clinical relevance of these interactions has not been studied in dogs. The combination with mixed agonist/antagonists (e.g. buprenorphine, butorphanol) and tramadol is not advisable, because the analgesic effect of a pure agonist may be theoretically reduced in such circumstances. See also section 4.3. 4.9 Amounts to be administered and administration route For oral administration.

The recommended dose of 80mg Tralieve for Dogs is 2-4 mg tramadol hydrochloride per kg body weight every 8 hours or as needed based on the intensity of pain. Minimum dosing interval is 6 hours. The recommended maximum daily dose is 16 mg/kg. As the individual response to tramadol is variable and depends partly on the dosage, the age of the patient, individual differences in pain sensitivity and general condition, the optimal dosing regimen should be individually tailored using the above dose and re-treatment interval ranges. The dog should be examined regularly by a veterinarian to assess if additional analgesia is subsequently required. Additional analgesia can be administered by increasing the tramadol dose until the maximum daily dose is reached, and/or by following a multimodal analgesic approach with the addition of other suitable analgesics. The most appropriate tablet strengths should be used in order to minimise divided tablets to be kept until the next dosing. Please note that this dosing table is intended as a guide for dispensing the product at the high end of the dose range: 4 mg/kg bodyweight. It states the number of tablets required to administer 4 mg tramadol hydrochloride per kg bodyweight.

80mg Tralieve is a POM-V (Pet Prescription is required)