Vetoryl 120mg Capsule for Dogs - per Capsule

Description

Vetoryl may only be supplied with a valid veterinary prescription issued by your vet. You should only purchase Vetoryl if you have or are in the process of arranging such a prescription. See information bar for further details.  

Vetoryl 120mg hard capsules for dogs. Hard gelatin capsules (ivory body/black cap) containing 120mg of trilostane. The ivory body is printed with the strength of the capsule.

Vetoryl is used in the treatment of Cushing's syndrome (excess production of corticosteroids from the adrenal glands) in dogs. Vetoryl may be used for treatment of both pituitary-dependent and adrenal-dependent hyperadrenocorticism in dogs. An accurate diagnosis of hyperadrenocorticism is essential.

Vetoryl Dosage and administration
For oral administration to dogs. (Information for the animal owner) Follow the dosage instructions given by your veterinary surgeon. In clinical studies an average starting dose of 6mg/kg of Vetoryl once daily was effective; however the dose of Vetoryl should be adjusted according to individual response as determined by monitoring by your veterinary surgeon. Most dogs were eventually stabilised on doses between 2-10 mg/kg/day. Administer orally once daily with food. Dosing in the morning is preferable as this will allow your veterinary surgeon to perform monitoring tests 4-6 hours following administration of the dose. Do not divide or open Vetoryl capsules. (Information for the veterinary surgeon)

Amounts to be administered: Practical starting doses are recommended as follows: Body weight (kg) Starting dose (mg) Dosage (mg/kg) >3 and <10 30 3-10 >10 and <20 60 3-6 >20 and <40 120 3-6 >40 120-240 3-6 The dose of Vetoryl should then be titrated according to individual response as determined by monitoring. Should symptoms not be adequately controlled for an entire 24 hour inter-dose period consideration should be given to increasing the daily dose of Vetoryl by as small an increment as possible and dividing it between morning and evening doses. A small number of animals may require doses significantly in excess of 10 mg per kg body weight per day. In these situations appropriate additional monitoring should be implemented. 10 mg capsules should be used in dogs that require particularly small doses of trilostane and to assist with dosage adjustments. Where there is no apparent response to treatment the diagnosis should be re-evaluated. Dose increases may be necessary.

Do not use Vetoryl in dogs weighing less than 3kg. Monitoring: Samples should be taken for biochemistry (including electrolytes) and an ACTH stimulation test pre-treatment and then at 10 days 4 weeks 12 weeks and thereafter every 3 months following initial diagnosis and after each dose adjustment. It is imperative that ACTH stimulation tests are performed 4-6 hours post-dosing to enable accurate interpretation of results. Regular assessment of the clinical progress of the disease should also be made at each of the above time points.

Legal category
Vetoryl is a POM-V (Pet Prescription Required)